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“Eat more fiber” is dietary advice that’s earned the right of repetition. High-fiber diets are linked to lower rates of heart disease and certain types of cancer, along with the daily bonus of keeping our digestive system running efficiently.

New research suggests another potentially big benefit: high-fiber diets may set off a chemical cascade resulting in reduced brain inflammation, which in turn could mean less cognitive decline and memory loss with age, and decreased risk of neurodegenerative diseases.

This was a mouse study, so it carries the caveat of “not yet tested in humans” – but as an initial look into the fiber-brain connection, the results are important.

Researchers started in the intestines by focusing on a short-chain fatty acid called butyrate, which is produced by bacteria that ferment fiber in the gut. Previous research found that a drug form of butyrate reduced tissue inflammation in mice and boosted the rodents’ memory. To find out if a diet high in fiber would have similar effects to the drug form of butyrate, the researchers fed young and aging mice high- and low-fiber diets and then tested their butyrate blood levels and assessed their levels of intestinal inflammation.

The results showed that a high-fiber diet delivered effects comparable to the drug by elevating butyrate and other short-chain fatty acids in both the young and old mice. The researchers noted that the high-fiber diet lowered intestinal inflammation in the older mice to levels indistinguishable from the young mice (which says a lot for the effects of a high-fiber diet even apart from other benefits).

Next, the researchers ran a genetic test on the mice and found that those fed a high-fiber diet also had reduced inflammation in their brain’s immune cells, known as microglia, which account for about 15% of all cells in the brain. Inflammation in microglia is thought to be one of the chief causes of cognitive decline as we age.

The researchers think this benefit came from the process that began with eating a high-fiber diet eventually reducing an inflammatory chemical known as interleukin-1β, which previous studies have linked with Alzheimer’s disease.

So the summary of the process revealed by this study looks like this: eating a high-fiber diet resulted in more short-chain fatty acids in the gut, including butyrate, which reduced intestinal inflammation, with the eventual effect of reducing brain-tissue inflammation. Reduced brain inflammation is linked to less cognitive decline and lower risk of dementia with age.

If these effects hold true in humans, the imperative to eat more fiber from sources like fruits, vegetables, nuts, seeds, beans and whole grains will be even more vital, particularly for older adults. And the results further reinforce a finding that’s turning up in study after study: what’s healthy for the heart is also generally healthy for the brain, and reducing inflammation is critically important for both.

“What you eat matters,” said corresponding study author Rodney Johnson, head of the Department of Animal Sciences at the University of Illinois at Urbana-Champaign. “We know that older adults consume 40% less dietary fiber than is recommended. Not getting enough fiber could have negative consequences for things you don’t even think about, such as connections to brain health and inflammation in general.”

The study was published in the journal Frontiers in Immunology.

You can find David DiSalvo on Twitter, Facebook, Google Plus, and at his website, daviddisalvo.org.

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” Consume more fiber” is dietary suggestions that’s made the right of repeating. High-fiber diet plans are connected to lower rates of heart problem and particular kinds of cancer, together with the day-to-day perk of keeping our digestion system running effectively.

New research study recommends another possibly huge advantage: high-fiber diet plans might trigger a chemical waterfall leading to minimized brain swelling, which in turn might imply less cognitive decrease and amnesia with age, and reduced danger of neurodegenerative illness.

This was a mouse research study, so it brings the caution of “not yet evaluated in human beings”– however as a preliminary check out the fiber-brain connection, the outcomes are very important.

Scientist began in the intestinal tracts by concentrating on a short-chain fat called butyrate, which is produced by germs that ferment fiber in the gut. Previous research study discovered that a drug kind of butyrate minimized tissue swelling in mice and improved the rodents’ memory. To learn if a diet plan high in fiber would have comparable impacts to the drug kind of butyrate, the scientists fed young and aging mice high- and low-fiber diet plans and after that evaluated their butyrate blood levels and evaluated their levels of intestinal tract swelling.

(********** )(************ )The outcomes revealed that a high-fiber diet plan provided impacts similar to the drug by raising butyrate and other short-chain fats in both the young and old mice. The scientists kept in mind that the high-fiber diet plan decreased intestinal tract swelling in the older mice to levels equivalent from the young mice (which states a lot for the impacts of a high-fiber diet plan even apart from other advantages).

Next, the scientists ran a hereditary test on the mice and discovered that those fed a high-fiber diet plan likewise had actually minimized swelling in their brain’s immune cells, called microglia, which represent about 15% of all cells in the brain. Swelling in microglia is believed to be among the primary reasons for cognitive decrease as we age.

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The scientists believe this advantage originated from the procedure that started with consuming a high-fiber diet plan ultimately minimizing an inflammatory chemical called interleukin-1β, which previous research studies have actually related to Alzheimer’s illness.

So the summary of the procedure exposed by this research study appears like this: consuming a high-fiber diet plan led to more short-chain fats in the gut, consisting of butyrate, which minimized intestinal tract swelling, with the ultimate impact of minimizing brain-tissue swelling. Decreased brain swelling is connected to less cognitive decrease and lower danger of dementia with age.

If these impacts apply in human beings, the essential to consume more fiber from sources like fruits, veggies, nuts, seeds, beans and entire grains will be much more important, especially for older grownups. And the outcomes even more enhance a finding that’s showing up in research study after research study: exactly what’s healthy for the heart is likewise normally healthy for the brain, and minimizing swelling is seriously essential for both.

” Exactly what you consume matters,” stated matching research study author Rodney Johnson, head of the Department of Animal Sciences at the University of Illinois at Urbana-Champaign. “We understand that older grownups take in 40% less dietary fiber than is advised. Not getting sufficient fiber might have unfavorable effects for things you do not even consider, such as connections to brain health and swelling in basic.”

The research study was released in the journal Frontiers in Immunology

You can discover David DiSalvo on Twitter, Facebook, Google Plus, and at his site, daviddisalvo.org

” readability =”80
7361536321″ >

“Consume more fiber” is dietary suggestions that’s made the right of repeating. High-fiber diet plans are connected to lower rates of heart problem and particular kinds of cancer, together with the day-to-day perk of keeping our digestion system running effectively.

New research study recommends another possibly huge advantage: high-fiber diet plans might trigger a chemical waterfall leading to minimized brain swelling, which in turn might imply less cognitive decrease and amnesia with age, and reduced danger of neurodegenerative illness.

This was a mouse research study, so it brings the caution of “not yet evaluated in human beings”– however as a preliminary check out the fiber-brain connection, the outcomes are very important.

Scientists began in the intestinal tracts by concentrating on a short-chain fat called butyrate , which is produced by germs that ferment fiber in the gut. Previous research study discovered that a drug kind of butyrate minimized tissue swelling in mice and improved the rodents’ memory. To learn if a diet plan high in fiber would have comparable impacts to the drug kind of butyrate, the scientists fed young and aging mice high – and low-fiber diet plans and after that evaluated their butyrate blood levels and evaluated their levels of intestinal tract swelling.

The outcomes revealed that a high-fiber diet plan provided impacts similar to the drug by raising butyrate and other short-chain fats in both the young and old mice. The scientists kept in mind that the high-fiber diet plan decreased intestinal tract swelling in the older mice to levels equivalent from the young mice (which states a lot for the impacts of a high-fiber diet plan even apart from other advantages).

Next, the scientists ran a hereditary test on the mice and discovered that those fed a high-fiber diet plan likewise had actually minimized swelling in their brain’s immune cells, called microglia, which represent about 15 % of all cells in the brain. Swelling in microglia is believed to be among the primary reasons for cognitive decrease as we age.

The scientists believe this advantage originated from the procedure that started with consuming a high-fiber diet plan ultimately minimizing an inflammatory chemical called interleukin-1β , which previous research studies have actually related to Alzheimer’s illness.

So the summary of the procedure exposed by this research study appears like this: consuming a high-fiber diet plan led to more short-chain fats in the gut, consisting of butyrate, which minimized intestinal tract swelling, with the ultimate impact of minimizing brain-tissue swelling. Decreased brain swelling is connected to less cognitive decrease and lower danger of dementia with age.

If these impacts apply in human beings, the essential to consume more fiber from sources like fruits, veggies, nuts, seeds, beans and entire grains will be much more important, especially for older grownups. And the outcomes even more enhance a finding that’s showing up in research study after research study: exactly what’s healthy for the heart is likewise normally healthy for the brain, and minimizing swelling is seriously essential for both.

“Exactly what you consume matters,” stated matching research study author Rodney Johnson, head of the Department of Animal Sciences at the University of Illinois at Urbana-Champaign. “We understand that older grownups take in 40 % less dietary fiber than is advised. Not getting sufficient fiber might have unfavorable effects for things you do not even consider, such as connections to brain health and swelling in basic.”

The research study was released in the journal Frontiers in Immunology

You can discover David DiSalvo on Twitter , Facebook , Google Plus , and at his site, daviddisalvo.org

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